The RelieVRx program—Now approved for patients with chronic lower back pain4

The RelieVRx program is indicated as adjunctive treatment for patients with moderate to severe cLBP lasting longer than 3 months.1

Clinically evaluated1,2

The efficacy and safety of the RelieVRx program were evaluated in a randomized, controlled, double-blind trial in patients with cLBP vs a non-immersive control (ShamVR).

188 participants from 40 states took part in the 56 session program clinical trial

After completing a baseline survey, and at least 1 of 3 pain surveys during the 2-week pre-treatment period, participants were randomized 1:1 to the RelieVRx program orShamVR treatment groups.

RelieVRx headset and content

(n=94)

Multimodal, skills-based, self-management VR program

Inclusion criteria1,2

Participants ranged in age from 18-85 years with self-reported non-malignant chronic lower back pain for at least 3 months' duration and with an average pain intensity of >4/10 over the past month based on the Defense and Veterans Pain Rating Scale*

Baseline characteristics2

51.5yrs
SD=13.1
Average age
5/10
SD=1.2
Average pain intensity
67%
Duration ≥5 years
History of back pain
No group differences were found for any baseline variable or treatment engagement (P≥.082).
*The Defense and Veterans Pain Rating Scale (DVPRS 2.0) is a pain assessment tool that utilizes a numerical rating scale to measure how much pain interferes with usual activity and sleep, and affects mood and contributes to stress.2

Proven pain reduction

At the end of the 56 session program, significant pain reduction was seen by those who used RelieVRx compared to the non-immersive headset.1,2

Reduction in1
Pain intensity (P<.001)
%
%
Interference with activity (P=.021)
%
%
Interference with sleep (P=.021)
%
%
Interference with mood (P=.021)
%
%
Interference with stress (P=.021)
%
%

RelieVRx

Sham VR

2/3 Patients icon

Nearly 2 out of 3 patients (65%) in the treatment group had a clinically meaningful* reduction in pain intensity2

71% reduction icon

Nearly half of patients (46%) in the treatment group experienced a 71% reduction in pain intensity on average2†

See the publication
*≥30% reduction in pain intensity.2†
Calculated from a group with ≥50% reduction in pain intensity.2

Lasting pain relief over time

Significant pain relief was sustained at 3 months3

Reduction in
Pain intensity (P=.0054)
%
%
Interference with activity (P=.0265)
%
%
Interference with sleep (P=.0389)
%
%
Interference with mood (P=.1067)
%
%
Interference with stress (P=.0128)
%
%

RelieVRx

Sham VR

Patients rated the RelieVRx program as engaging and easy to use

4.32 Satisfaction rating
Engagement and satisfaction

Participants were highly engaged, completing 77% or more of the RelieVRx program and Sham VR programs2

Participants were very satisfied with the RelieVRx program, with a 4.32 satisfaction rating on a 5-point scale2

85% of participants expressed a desire to continue with the program after treatment3

A+ usability
Ease of use

The RelieVRx program was rated 84.33/100 on the System Usability Scale which is considered an A+ in usability according to industry benchmarks2

It was ranked as easier to use than a bank ATM4

Prescription bottle icon
Medication use

18% of the participants stopped taking over-the-counter analgesics at the end of the treatment program, while no reduction was reported among the Sham VR participants (P=.01)2

Learn about the RelieVRx device and established curriculum.

Discover RelieVRx Therapy

Indication for Use

The RelieVRx program is a prescription-use immersive virtual reality system intended to provide adjunctive treatment based on cognitive behavioral therapy skills and other evidence-based behavioral methods for patients (age 18 and older) with a diagnosis of chronic lower back-pain (defined as moderate to severe pain lasting longer than three months). The device is intended for in-home use for the reduction of pain and pain interference associated with chronic lower back pain.

Contraindications

There are no known contraindications.

References

  1. RelieVRx [instructions for use]. Van Nuys, CA: AppliedVR, Inc.; 2021.
  2. Garcia LM, Birckhead BJ, Krishnamurthy P, et al. An 8-week self-administered at-home behavioral skills-based virtual reality program for chronic low back pain: double-blind, randomized, placebo-controlled trial conducted during COVID-19. J Med Internet Res. 2021;23(2):e26292. doi:10.2196/26292
  3. Garcia LM, Birckhead BJ, Krishnamurthy P, et al. Three-month follow-up results of a double-blind, randomized placebo-controlled trial of 8-week self-administered at-home behavioral skills-based virtual reality (VR) for chronic low back pain. J Pain. 2021.
  4. AppliedVR Press Release. Accessed January 18, 2022.

RelieVRx was formerly known as EaseVRx.